Huge region up in USA is Appalachia

While searching our database we found 1 possible solution for the: Huge region up in USA is Appalachia crossword clue. This crossword clue was last seen on 13 October 2021 The Sun Cryptic Crossword puzzle. The solution we have for Huge region up in USA is Appalachia has a total of 4 letters.

Answer

1A
2S
3I
4A

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If you have already solved this crossword clue and are looking for the main post then head over to The Sun Cryptic Crossword 13 October 2021 Answers